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Publications

2015

Multicomponent Reactions in Antimitotic Drug Discovery
A. Cores, C. Carbajales, A. Coelho

2014

Structure-Based Design of New KSP-Eg5 Inhibitors Assisted by a Targeted Multicomponent Reaction
C. Carbajales, M.A. Prado, H. Gutiérrez de Terán, A. Cores, J. Azuaje, S. Novio, M.J. Núñez, B. Fernández García, E. Sotelo, X García Mera, P. Sánchez Lazo, M. Freire Garabal, A. Coelho

Ugi-Based Approaches to Quinoxaline Libraries
J. Azuaje, A. El Maatougui, X. García Mera, E. Sotelo

2013

Discovery of 3,4-Dihydropyrimidin-2(1H)-ones As a Novel Class of Potent and Selective A2B Adenosine Receptor Antagonists
A. Crespo, A. El Maatougui, P. Biagini, J. Azuaje, A. Coelho, J. Brea, M.I. Loza; M.I. Cadavid, X. GarcíaMera, H. Gutierrez de Terán, E. Sotelo

Selective and potent adenosine A3 receptor antagonists by methoxyaryl substitution on the N-(2,6-diarylpyrimidin-4-yl)acetamide scaffold
V. Yaziji, D. Rodríguez, A.Coelho, X. García-Mera, A. El Maatougui, J. Brea, M. I. Loza, M. I. Cadavid, H. Gutiérrez-de-Terán, E. Sotelo

Multicomponent Assembly of Diverse Pyrazin-2(1H)-one Chemotypes
J. Azuaje; A. El Maatougui; J.M. Pérez-Rubio; A. Coelho; F. Fernández; E. Sotelo

Copper-Catalyzed Huisgen 1,3-Dipolar Cycloaddition under Oxidative Conditions: Polymer-Assisted Assembly of 4-Acyl-1-Substituted-1,2,3-Triazoles
P.M. Diz, A. Coelho, A. El Maatougui, J. Azuaje, O. Caamaño, A. Gil, E. Sotelo

Three-Component Assembly of Structurally Diverse 2-Aminopyrimidine-5-carbonitriles
C. Val, V. Jaziji, A. Coelho, J. Auaje, A. Maatougui, C. CArbajales, E. Sotelo

2012

Discovery and Preliminary SAR of 5-Arylidene-2,2-Dimethyl-1,3-Dioxane-4,6-Diones as Platelet Aggregation Inhibitors
El Maatougui, A.; Azuaje, J.; Coelho, A.; Cano, E.; Yañez, M.; Yaziji, V.; Carbajales, C.; Sotelo. E.

2011

Silica-Supported Aluminum Chloride-Assisted Solution Phase Synthesis of Pyridazinone-Based Antiplatelet Agents
A.El Maatougui, J. Azuaje, E. Sotelo, O. Caamaño, A.Coelho