Publicaciones
2022
Selection of AmpC β-Lactamase Variants and Metallo-β-Lactamases Leading to Ceftolozane/Tazobactam and Ceftazidime/Avibactam Resistance during Treatment of MDR/XDR Pseudomonas aeruginosa Infections
2021
Molecular Basis of Bicyclic Boronate β-Lactamase Inhibitors of Ultrabroad Efficacy – Insights From Molecular Dynamics Simulation Studies
Crambescin C1 Acts as A Possible Substrate of iNOS and eNOS Increasing Nitric Oxide Production and Inducing In Vivo Hypotensive Effect
6-Halopyridylmethylidene Penicillin-Based Sulfones Efficiently Inactivate the Natural Resistance of Pseudomonas aeruginosa to β-Lactam Antibiotics
Bicyclic Boronate β‐Lactamase Inhibitors: The Present Hope against Deadly Bacterial Pathogens
Activity of imipenem, meropenem, cefepime, and sulbactam in combination with the β-lactamase inhibitor ln-1-255 against acinetobacter spp
Molecular mechanisms driving in vivo development of OXA-10-mediated resistance to ceftolozane/tazobactam and ceftazidime/avibactam during treatment of extensively drug-resistant Pseudomonas aeruginosa infection
2020
Characterization of the Locally Excited and Charge-transfer States of the Anticancer Drug Lapatinib by Ultrafast Spectroscopy and Computational Studies
Protein Binding of Lapatinib and Its N- and O-Dealkylated Metabolites Interrogated by Fluorescence, Ultrafast Spectroscopy and Molecular Dynamics Simulations
Molecular and biochemical insights into the in vivo evolution of AmpC-mediated resistance to ceftolozane-tazobactam during treatment of a multidrug-resistant Pseudomonas aeruginosa infection