31/07/2014
The research group of Ricardo Riguera y Eduardo Fdez.-Megía, in collaboration with the groups of Capan, Couvreur y Dalkara (Dpt, of Pharmaceutical Technology, Hacettepe University, Ankara), Capan, Couvreur, and Dalkara in two papers about the use of PEGylated chitosan in drug delivery.
With the aim of increasing the poor solubility of CS at physiological pH, the CIQUS researchers prepared PEG-grafted CS copolymers (CS-g-PEG). The decoration of CS-g-PEG with ligands by means of efficient coupling technologies allows the preparation of functionalized nanostructures for advanced applications in drug delivery.
An Aquaporin 4 Antisense Oligonucleotide Loaded, Brain Targeted Nanoparticulate System Design
S. Kozlu, S. Caban, F. Yerlikaya, E. Fernandez-Megia, R. Novoa-Carballal, R. Riguera, M. Yemisci, Y. Gursoy-Ozdemir, T. Dalkara,P. Couvreur, Y. Capan.
GATG Dendrimers and PEGylated Block Copolymers: from Synthesis to Bioapplications
A. Sousa Herves, R. Novoa Carballal, R. Riguera, E. Fernández Megía
